Inhibition of inducible nitric oxide synthase gene expression (iNOS) and cytotoxic activity of Salvia sclarea L. essential oil
نویسندگان
چکیده
منابع مشابه
EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE GENE (iNOS) STIMULATED BY HYDROGEN PEROXIDE IN HUMAN ENDOTHELIAL CELLS
Inducible nitric oxide synthase (iNOS) gene expresses a calcium calmudolin-independent enzyme which can catalyse NO production from L-arginine. The induction of iNOS activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (LPS). Previous studies indicated that all nitric oxide synthases (NOS) activated in human umbilical vein endot...
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Objective(s): Nitric oxide (NO), a product of inducible nitric oxide synthase (iNOS), contributes in germ cell apoptosis. This study was aimed to evaluate the effects of Aloe vera gel (AVG) on male Wistar rat reproductive organ, serum NO level, and expression of iNOS gene in leydig cells. Materials and Methods:Adult male Wistar rats (n=36) were used for experiments in three groups. The experim...
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inducible nitric oxide synthase (inos) gene expresses a calcium calmudolin-independent enzyme which can catalyse no production from l-arginine. the induction of inos activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (lps). previous studies indicated that all nitric oxide synthases (nos) activated in human umbilical vein endot...
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The essential oil from the aerial parts of Salvia sclarea L., growing wild in Tajikistan, were obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. A total of 59 compounds were identified representing 94.2% of total oil composition. Major components of the essential oil were linalyl acetate (39.2%), linalool (12.5%), germacrene D (11.4%), α-terpineol (5.5%), ger...
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ژورنال
عنوان ژورنال: Journal of King Saud University - Science
سال: 2016
ISSN: 1018-3647
DOI: 10.1016/j.jksus.2015.11.001